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Fenobarbital uzet istovremeno može dovesti do aditivnog efekta na CNS. Povećan je rizik od sedacije i respiratorne depresije. Poznato je da fenobarbital indukuje CYP3A4 enzim i ubrzava metabolizam diazepama u jetri, što smanjuje efekat diazepama.

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Actual physical dependence might lead to withdrawal Uncomfortable side effects if therapy is stopped instantly. On the other hand, significant withdrawal Unwanted side effects can generally be prevented by slowly reducing the dose around a time period before cure is stopped fully.

Antivirusni lekovi inhibiraju CYP3A4 metabolički place diazepama. Povećan je rizik od sedacije i respiratorne depresije. Zbog toga treba izbegavati istovremenu primenu.

Respiratory rate: Your health practitioner will keep an eye on your respiration level during treatment method to ensure it’s not much too small.

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Smanjenje ili povećanje koncentracije fenitoina u serumu. Neophodno je pažljivo pratiti koncentracije fenitoina pri uvođenju ili obustavi diazepama.

Tend not to transform your dose or quickly stop working with this medication devoid of initially examining with your medical professional. Your health care provider might want you to gradually reduce the quantity you happen to be working with ahead of stopping it fully.

Za postizanje anksiolitičkog efekta treba dati najnižu efektivnu dozu; lečenje ne treba da traje duže od four nedelje i lek treba postepeno povlačiti iz terapije.

Applying this drugs with any of the website following medicines is normally not proposed, but might be necessary occasionally. If both medicines are prescribed collectively, your doctor may change the dose or how frequently you utilize just one or equally in the medicines.

Tell people that occasionally, sufferers taking benzodiazepines have formulated a protracted withdrawal syndrome with withdrawal signs and symptoms Long lasting months to a lot more than 12 months. Instruct people that discontinuation or dosage reduction of diazepam tablets might require a sluggish taper (see WARNINGS: Dependence and Withdrawal Reactions and DRUG ABUSE AND DEPENDENCE).

These drugs help it become harder for your body to soak up diazepam. If you're taking them together, you may not get the entire dose of diazepam, and it might not operate also. These drugs include things like: